Rothe or Roethe is a surname. Notable people with the surname include:
Utz Rothe, Austrian artistBendt Rothe, Danish actorDavid Rothe, Irish Roman Catholic bishopJohannes Rothe, (1628-1702), prophetic preacher and Fifth Monarchist.Heinrich August Rothe (1773–1842), German mathematicianMechtild Rothe (1947), German politicianRichard Rothe (1799–1867), German theologianRichard Roethe (1865–1944), German military officerSjur Røthe (1988), Norwegian cross-country skierEdward J. Roethe, American politicianHenry Edgar Roethe (1866–1939), American politicianRothé, a form of cattle in various roleplaying games