The roads of Cincinnati, Ohio include three major interstate highways, one interstate bypass and one interstate spur and six U.S. highways.
Cincinnati is served by three major interstate highways, one beltway, and one spur.
Interstate 71 splits off from Interstate 75 near the Brent Spence Bridge and heads eastward through Fort Washington Way. It junctions Interstate 471 before heading northeast towards Mt. Adams and Walnut Hills. It has major junctions with SR 562 (Norwood Lateral) and SR 126 (Ronald Reagan Cross County Highway).
Interstate 74 begins at Interstate 75 west of downtown and proceeds towards Indiana. Its only primary junction is with Interstate 275.
Interstate 75 is a north–south route through the Mill Creek valley. It enters from Kentucky on the Brent Spence Bridge, where it overlaps Interstate 71. Interstate 71 splits eastward at an elevated junction immediately north of the Ohio River. Interstate 75 has major junctions with Interstate 74, SR 562 (Norwood Lateral) and SR 126 (Ronald Reagan Cross County Highway).
Interstate 275 is an outer-belt of Cincinnati. It has major junctions with all major interstate highways that radiate from the city.
Interstate 471 is a spur that begins at the eastern terminus of Fort Washington Way and proceeds southward into Kentucky, where it terminates at the junction of Interstate 275 and US 27.
US 22
US 25 (only exists on the Clay Wade Bailey Bridge within Ohio, and is Kentucky maintained)
US 27
US 42
US 50
Columbia Parkway
Sixth Street Expressway
US 52
US 127
SR 3 (Montgomery Rd.)
SR 4 (Paddock Rd.)
SR 125 (Beechmont Avenue/Ohio Pike)
SR 126 (Ronald Reagan Cross County Highway)
SR 264 (Glenway Ave.)
SR 561
SR 562 (Norwood Lateral)
Central Parkway
Bypass 50 ran concurrently with State route 126 heading east from Springfield Pike (Route 4) in Woodlawn and was known as Glendale-Milford Road then Pfeiffer Road after crossing Kenwood Road. Continuing to its Pfieffer Road terminus at Montgomery Road the route turned south then east at Remington Road. The road changed names back to Glendale-Milford entering Miamiville, then turned south heading through Camp Dennison before terminating at Route 50 (Wooster Pike) in Terrace Park, yards from the Hamilton-Clermont County line. The route was discontinued in 1997 when the Ronald Reagan highway was opened and designated at State Highway 126
