Rahul Sharma (Editor)

Ribosylnicotinamide kinase

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EC number
  
2.7.1.22

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
9030-61-9

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a ribosylnicotinamide kinase (EC 2.7.1.22) is an enzyme that catalyzes the chemical reaction

Contents

ATP + N-ribosylnicotinamide ADP + nicotinamide ribonucleotide

Thus, the two substrates of this enzyme are ATP and N-ribosylnicotinamide, whereas its two products are ADP and nicotinamide ribonucleotide.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:N-ribosylnicotinamide 5'-phosphotransferase. This enzyme is also called ribosylnicotinamide kinase (phosphorylating). This enzyme participates in nicotinate and nicotinamide metabolism.

Health

Studies show potential for obesity treatment and for longer healthier life. Ribosylnicotinamide kinasee seems to activate similar genes that Resveratrol does.

Food

The enzyme can be found in milk and beer. Since the molecules are difficult to detect, it is expected that there is a lot more food products containing ribosylnicotinamide kinase.

References

Ribosylnicotinamide kinase Wikipedia