Red Devil Lye is a household product made of sodium hydroxide (lye), introduced around the start of the 20th century.
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Household uses
Household uses of Red Devil Lye included soap making and cleaning drains.
Use in magic
In addition to its practical uses, Red Devil Lye was also used as a hoodoo magical ingredient in the American South, where it could be used to magically protect a property from trespassers by burying cans of the product in the four corners of a property.
References
Red Devil Lye Wikipedia(Text) CC BY-SA