Species Human Entrez 8986 | Human Mouse Ensembl ENSG00000162302 | |
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Aliases RPS6KA4, MSK2, RSK-B, S6K-alpha-4, ribosomal protein S6 kinase A4 External IDs MGI: 1930076 HomoloGene: 69288 GeneCards: RPS6KA4 | ||
Ribosomal protein S6 kinase alpha-4 is an enzyme that in humans is encoded by the RPS6KA4 gene.
Contents
Function
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-Fos. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Interactions
RPS6KA4 has been shown to interact with MAPK14.
References
RPS6KA4 Wikipedia(Text) CC BY-SA