Species Human Entrez 6047 | Human Mouse Ensembl ENSG00000063978 | |
 | ||
Aliases RNF4, SLX5, SNURF, RES4-26, ring finger protein 4 External IDs MGI: 1201691 HomoloGene: 37711 GeneCards: RNF4 | ||
RING finger protein 4 is a protein that in humans is encoded by the RNF4 gene.
The protein encoded by this gene contains a RING finger domain and acts as a transcription factor. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ1 is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis.
Interactions
RNF4 has been shown to interact with TCF20, PATZ1 and Androgen receptor.
References
RNF4 Wikipedia(Text) CC BY-SA