Species Human Entrez 64320 | Human Mouse Ensembl ENSG00000163481 | |
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Aliases RNF25, AO7, ring finger protein 25 External IDs MGI: 1890215 HomoloGene: 11193 GeneCards: RNF25 | ||
E3 ubiquitin-protein ligase RNF25 is an enzyme that in humans is encoded by the RNF25 gene.
Contents
Function
The protein encoded by this gene contains a RING finger motif. The mouse counterpart of this protein has been shown to interact with Rela, the p65 subunit of NF-kappaB (NFKB), and modulate NFKB-mediated transcription activity. The mouse protein also binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination.
Interactions
RNF25 has been shown to interact with RELA.
References
RNF25 Wikipedia(Text) CC BY-SA