RNA polymerase V

RNA polymerase V is a multisubunit plant specific RNA polymerase found in nucleus. Together with RNA polymerase IV required for normal function and biogenesis of small interferring RNA (siRNA). Pol V is involved in siRNA-directed DNA methylation pathway which leads to heterochromatic silencing.

RNA polymerase V is composed of 12 subunits that are paralogous to RNA polymerase II subunits. Two largest subunits (catalytic site) is the most conserved region sharing similarity with eukaryotic and bacterial polymerases.