Species Human Entrez 6016 | Human Mouse Ensembl ENSG00000143622 | |
 | ||
Aliases RIT1, NS8, RIBB, RIT, ROC1, Ras like without CAAX 1 External IDs MGI: 108053 HomoloGene: 56003 GeneCards: RIT1 | ||
GTP-binding protein Rit1 is a protein that in humans is encoded by the RIT1 gene.
Contents
Function
RIT belongs to the RAS (HRAS; MIM 190020) subfamily of small GTPases (Hynds et al., 2003).[supplied by OMIM]
Clinical significance
Mutations in RIT1 are associated to Noonan syndrome .
Interactions
RIT1 has been shown to interact with KLHL12 and Merlin.
References
RIT1 Wikipedia(Text) CC BY-SA