RIT1

Updated on Dec 11, 2024

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Species Human Entrez 6016		Human Mouse Ensembl ENSG00000143622

Aliases RIT1, NS8, RIBB, RIT, ROC1, Ras like without CAAX 1 External IDs MGI: 108053 HomoloGene: 56003 GeneCards: RIT1

GTP-binding protein Rit1 is a protein that in humans is encoded by the RIT1 gene.

Function

RIT belongs to the RAS (HRAS; MIM 190020) subfamily of small GTPases (Hynds et al., 2003).[supplied by OMIM]

Mutations in RIT1 are associated to Noonan syndrome .

RIT1 has been shown to interact with KLHL12 and Merlin.

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