Puneet Varma (Editor)

RIMS1

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Species
  
Human

Entrez
  
22999

Human
  
Mouse

Ensembl
  
ENSG00000079841

RIMS1

Aliases
  
RIMS1, CORD7, RAB3IP2, RIM, RIM1, regulating synaptic membrane exocytosis 1

External IDs
  
MGI: 2152971 HomoloGene: 128399 GeneCards: RIMS1

Regulating synaptic membrane exocytosis protein 1 is a protein that in humans is encoded by the RIMS1 gene.

Contents

Function

RAB3A (MIM 179490), a member of the Ras superfamily of genes, is a synaptic vesicle protein that regulates synaptic vesicle exocytosis. MUNC13 (UNC13; MIM 605836) and its isoforms are required for priming synaptic vesicles for exocytosis. The RIM family of active zone proteins likely function as protein scaffolds that help regulate vesicle exocytosis during short-term plasticity.[supplied by OMIM]

Interactions

RIMS1 has been shown to interact with:

  • ERC2,
  • RAB3A,
  • UNC13A,
  • UNC13B, and
  • YWHAH.
  • References

    RIMS1 Wikipedia