Aliases RGS7 Human Mouse Ensembl ENSG00000182901 | Species Human Entrez 6000 | |
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External IDs MGI: 1346089 HomoloGene: 2193 GeneCards: RGS7 | ||
Regulator of G-protein signaling 7 is a protein that in humans is encoded by the RGS7 gene.
RGS7 is highly enriched in the brain where it acts as a universal inhibitor of Gi/o-coupled GPCR. RGS7 is a GTPase-activating protein (GAP). It accelerates the GTP hydrolysis on G proteins determining their fast inactivation and acting as intracellular antagonists of GPCR signaling.
Interactions
RGS7 has been shown to interact with:
References
RGS7 Wikipedia(Text) CC BY-SA