Species Human Entrez 27342 | Human Mouse Ensembl ENSG00000154710 | |
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Aliases RABGEF1, RABEX5, RAP1, rabex-5, RAB guanine nucleotide exchange factor 1 External IDs MGI: 1929459 HomoloGene: 8720 GeneCards: RABGEF1 | ||
Rab5 GDP/GTP exchange factor is a protein that in humans is encoded by the RABGEF1 gene.
RABGEF1 forms a complex with rabaptin-5 (RABPT5; MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor for RAB5(RAB5A; MIM 179512) (Horiuchi et al., 1997).[supplied by OMIM]
References
RABGEF1 Wikipedia(Text) CC BY-SA