Species Human Entrez 5868 | Human Mouse Ensembl ENSG00000144566 | |
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Aliases RAB5A, RAB5, member RAS oncogene family External IDs MGI: 105926 HomoloGene: 68142 GeneCards: RAB5A | ||
Ras-related protein Rab-5A is a protein that in humans is encoded by the RAB5A gene.
Contents
Function
RAB5A localizes to early endosomes where it is involved in the recruitment of RAB7A and the maturation of these compartments to late endosomes. It drives the maturation of endosomes by transporting vacuolar (H+)-ATPases (V-ATPases) from trans-Golgi network to endocytic vesicles.
Interactions
RAB5A has been shown to interact with:
References
RAB5A Wikipedia(Text) CC BY-SA