Quimby is an English surname derived from a toponym such as Quenby. Notable people with the surname include:
Darius Quimby (died 1791), first American law enforcement officer killed in line of duty
Edith Quimby (1891–1982), American medical researcher and physicist
Fred Quimby (1883–1965), American cartoon producer, best known as a producer of Tom and Jerry cartoons
Harriet Quimby (1875–1912), the first female pilot in the United States
Phineas Quimby (1802–1866), a 19th-century American philosopher
Robert Quimby (born 1976), American astronomer
Shirley Leon Quimby (1893–1986), American physicist
William R. "Bill" Quimby (born 1936), American author