CAS Number 1400742-42-8 ChemSpider 29339967 3D model (Jmol) Interactive image | PubChem CID 71711120 Formula C25H24N2O2 Molar mass 384.47 g/mol | |
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Legal status CA: Schedule II
DE: Anlage II (Prohibited)
NZ: Temporary Class | ||
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QUCHIC (BB-22 or 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester) is a designer drug offered by online vendors as a cannabimimetic agent, and was first detected being sold in synthetic cannabis products in Japan in early 2013, and subsequently also in New Zealand. The structure of QUCHIC appears to utilise an understanding of structure-activity relationships within the indole class of cannabimimetics, although its design origins are unclear. QUCHIC, along with QUPIC, represents a structurally unique synthetic cannabinoid chemotype since it contains an ester linker at the indole 3-position rather than the precedented ketone of JWH-018 and its analogues, or the amide of SDB-001 and its analogues.
Contents
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Pharmacology
BB-22 acts as a full agonist with a binding affinity of 0.217nM at CB1 and 0.338nM at CB2 cannabinoid receptors.