EC number 3.1.3.74 | ExPASy NiceZyme view MetaCyc | |
In enzymology, a pyridoxal phosphatase (EC 3.1.3.74) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are pyridoxal 5'-phosphate and H2O, whereas its two products are pyridoxal and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is pyridoxal-5'-phosphate phosphohydrolase. Other names in common use include vitamine B6 (pyridoxine) phosphatase, PLP phosphatase, vitamin B6-phosphate phosphatase, and PNP phosphatase. This enzyme participates in vitamin B6 metabolism.
Structural studies
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 2CFR, 2CFS, 2CFT, 2OYC, 2P27, and 2P69.