Harman Patil (Editor)

Pure red cell aplasia

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Specialty
  
hematology

ICD-9-CM
  
284.8

eMedicine
  
med/1967

ICD-10
  
D60

DiseasesDB
  
29063

MeSH
  
D012010

Pure red cell aplasia (PRCA) or erythroblastopenia refers to a type of anemia affecting the precursors to red blood cells but not to white blood cells. In PRCA, the bone marrow ceases to produce red blood cells. The condition has been first described by Paul Kaznelson in 1922.

Contents

  • pallor
  • tachycardia
  • decreased activity
  • Causes

    Causes of PRCA include:

    Treatment

    PRCA is considered an autoimmune disease as it will respond to immunosuppressant treatment such as ciclosporin in many patients, though this approach is not without risk.

    It has also been shown to respond to treatments with Rituximab and Tacrolimus.

    References

    Pure red cell aplasia Wikipedia