Species Human Entrez 387357 | Human Mouse Ensembl n/a | |
Aliases THEMIS, C6orf190, C6orf207, GASP, SPOT, TSEPA, bA325O24.3, bA325O24.4, thymocyte selection associated External IDs MGI: 2443552 HomoloGene: 72287 GeneCards: THEMIS | ||
Protein THEMIS is a protein that in humans is encoded by the THEMIS gene.
Contents
Function
This protein plays a regulatory role in both positive and negative T cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells.
The name
THEMIS is an acronym for thymocyte-expressed-molecule. Themis is also the name of a Titan in Greek mythology who weighed the fates of humans, an apt choice since the protein is important in deciding the fate of the T cell during development.
References
Protein THEMIS Wikipedia(Text) CC BY-SA