EC number 5.3.99.3 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 52227-79-9 BRENDA BRENDA entry KEGG KEGG entry | |
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Prostaglandin E synthase (or PGE synthase) is an enzyme involved in eicosanoid and glutathione metabolism, a member of MAPEG family. It generates prostaglandin E (PGE) from prostaglandin H2.
The synthase generating PGE2 is a membrane-associated protein.
Isozymes
Humans express three prostaglandin-E synthase isozymes, each encoded by a separate gene:
References
Prostaglandin E synthase Wikipedia(Text) CC BY-SA