Preuss or Preuß is a German surname derived from Preussen, the German word for Prussia, and may refer to:
Charles Preuss (born 1803), surveyor and cartographer on Fremont expeditions in the American West
Christoph Preuß (born 1981), German football player
Hugo Preuß (1860–1925), German lawyer and liberal politician
Josefine Preuß (born 1986), German actress
Konrad Theodor Preuss (1869–1938), German ethnologist
Paul Preuss (author) (born 1942), American science-fiction author and science consultant for film companies
Paul Preuss (climber) (1886–1913), Austrian mountain climber
Ted Preuss (born 1962), American Fine Art Photographer
