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Pranlukast

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Trade names
  
Onon (オノン)

ATC code
  
R03DC02 (WHO)

CAS ID
  
103177-37-3

Routes of administration
  
Oral

Biological half-life
  
1.5 hours

Molar mass
  
481.503 g/mol

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AHFS/Drugs.com
  
International Drug Names

Metabolism
  
Hepatic (mainly CYP3A4)

Pranlukast (brand name Onon, オノン) is a cysteinyl leukotriene receptor-1 antagonist. This drug works similarly to Merck & Co.'s montelukast (Singulair). It is widely used in Japan.

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Medications of this class, which go under a variety of names according to whether one looks at the American, British or European system of nomenclature, have as their primary function the antagonism of bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.

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Medications of this group are normally used as an adjunct to the standard therapy of inhaled steroids with inhaled long- and/or short-acting beta-agonists. There are several similar medications in the group; all appear to be equally effective.

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References

Pranlukast Wikipedia