Polanco is a Spanish surname originating from the municipality of Polanco, Cantabria in Spain. Notable people with the surname include:
Jesús Polanco (1929–2007), Spanish businessman and founder of El Pais and Grupo PRISA. Ranked in Forbes' richest list 2006
Juan Hidalgo de Polanco (1614-1685), Spanish composer, father of the Spanish Opera and of the Zarzuela
Juan Alfonso de Polanco (1517-1576)- Spanish Jesuit Priest and secretary to Ignatius of Loyola
Polanco family, noble family from Santillana del Mar, Cantabria
Polanco (painters), two brothers active as painters in 17th century in Valencia, Spain
Alfonso Polanco, mayor of Palencia,Spain
Nicolás Manrique de Lara y Polanco, noble of the Marquesado de Lara
Eduardo Saenz de Buruaga y Polanco, Spanish military general
Tomas Polanco Alcantara, Venezuelan writer and historian
Antonio Botín Polanco, Spanish writer from Santander, Cantabria
Luis Polanco, Spanish governor of Toleto
Francisco Polanco, Spanish baroque painter of 17th century
Campuzano-Polanco, elite family from the colony of Santo Domingo
Gaspar Polanco Borbón, Dominican military and provisional president
Raymundo Polanco Alegría, Dominican Air Force military and businessman
Dalilah Polanco, Mexican actress
Amelia Vega Polanco, Miss Universe 2003
Santiago Polanco-Abreu (1920–1988), Puerto Rican politician
Miguel Angel Polanco (1941–2012), famous Salvadoran painter and sculptor
Richard G. Polanco, American Politician, former California State Senate Majority Leader
Mario Polanco, Guatemalan human rights activist
Plácido Polanco (born 1975), Dominican-American Major League Baseball infielder
Gregory Polanco (born 1991), Dominican Major League Baseball outfielder