Trisha Shetty (Editor)

Platelet storage pool deficiency

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Specialty
  
hematology

OMIM
  
185050

ICD-10
  
D69.1

MeSH
  
D010981

Platelet storage pool deficiency is a type of coagulopathy characterized by defects in the granules in platelets, particularly a lack of granular non-metabolic ADP. Patients with ADP deficient "Storage Pool Disease" present a prolonged bleeding time due to impaired aggregation response to fibrillar collagen.

It may involve the alpha granules or the dense granules.

Conditions

Examples include:

  • Platelet alpha-granules
  • Gray platelet syndrome
  • Quebec platelet disorder
  • Dense granules
  • δ-Storage pool deficiency
  • Hermansky–Pudlak syndrome
  • Chédiak–Higashi syndrome

    • References

    Platelet storage pool deficiency Wikipedia
    (Text) CC BY-SA