Latin granulum delta | Code TH H2.00.04.1.03006 | |
Dense granules (also known as dense bodies or delta granules) are specialized secretory organelles.
Contents
In unicellular organisms
They are found in animals and in unicellular organisms including Apicomplexa protozoans.
They are also found in Entamoeba.
Components
The dense granules of human platelets contain adenosine diphosphate (ADP), adenosine triphosphate (ATP), ionized calcium (which is necessary for several steps of the coagulation cascade), histamine and serotonin.
Clinical significance
A deficiency of CD63 can be associated with Hermansky-Pudlak syndrome.
References
Dense granule Wikipedia(Text) CC BY-SA