Platelet-rich fibrin (PRF) or leucocyte- and platelet-rich fibrin (L-PRF) is a second-generation PRP where autologous platelets and leucocytes are present in a complex fibrin matrix to accelerate the healing of soft and hard tissue and is used as a tissue-engineering scaffold for endodontics.
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Socket preservation
Socket preservation, a procedure to reduce bone loss after tooth extraction to preserve the dental alveolus (tooth socket) in the alveolar bone. A platelet-rich fibrin (PRF) membrane containing bone growth enhancing elements can be stitched over the wound or a graft material or scaffold is placed in the socket of an extracted tooth at the time of extraction. The socket is then directly closed with stitches or covered with a non-resorbable or resorbable membrane and sutured.
Sinus lift
A platelet-rich fibrin can be used if a sinus lift is required for a dental implant.
Guided bone and tissue regeneration
PRF is used in guided bone and tissue regeneration
Regenerative endodontics
PRF enhances alveolar bone augmentation and necrotic dental pulp and open tooth apex can be revitalized in regenerative endodontics with platelet-rich fibrin.