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Plakophilin 3

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Aliases
  
PKP3

Human
  
Mouse

Ensembl
  
ENSG00000184363

Species
  
Human

Entrez
  
11187

Plakophilin-3

External IDs
  
MGI: 1891830 HomoloGene: 5200 GeneCards: PKP3

Plakophilin-3 is a protein that in humans is encoded by the PKP3 gene.

Contents

Function

This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways.

Interactions

PKP3 has been shown to interact with:

  • DSC3,
  • DSG1,
  • DSG2 and
  • DSG3.

    • References

    Plakophilin-3 Wikipedia
    (Text) CC BY-SA


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