Pitafi (پتافي) originally the descendants of Hazrat Ameer Hamza, a branch of Baloch tribes are mostly living in District Ghotki, Sindh, Tando Allahyar, Sindh, Badin Sindh ,Khairpur Mir's, Sindh, Rajanpur, Punjab, Muzafar Garh, Punjab, Dera Ismail Khan, NWFP and are scattered in other parts of Pakistan. It is said that Pitafi tribe was living near Petaf river in Iranian Balochistan, and were known by the people as "petafi", which means the people living at Petaf. Centuries ago some of them travelled to Balochistan (Pakistan) and then moved to Punjab and then entered Sindh. The chief of Pitafi tribe Sardar Mir Gul Muhammad Khan (Awal) was the General of their tribal army. He was supporting Abbasis of Bahawalpur State.
Pitafi is a Baloch tribe which resides throughout various regions of Pakistan. The name appears to mean "southern". Pitafi was noted as a sub-tribe or branch in 1883. and prominently in Sindh Province, whereas the total number of residents is unclear in both these provinces. They are said to be Rinds that joined the Gurchani, conversely the Gurchani are said to be Rind Balochs by paternal descent, but descended from Doda, a member of the Deh, who married a Rind girl, and became a follower of Chakur Rind (or Rhind). Doda's son Ghorish returned to the area and founded the tribe, four septs being founded by his sons. The Pitafi were present in the Dera Ghazi Khan district in the nineteenth century, in the vicinity of Harand. Around the 1860s there was a feud with the Doorkani, the mokkudum of the Doorkani, Tajossh Khan was killed in a border fight by Wuzeer Pitafi. Tajossh's son, Sorab succeeding him, attempted to avenge his father but was captured by Dewan Moolraj's troops and held captive for nine years in Mooltan. During this period his uncle, Mitta Khan managed the tribe, and, on Sorab's return, Sorab resigned in his uncle's favour. Wuzeer Pitafi healed the breach in the traditional Baloch manner, by giving his daughter's hand in marriage to Sorab, who he also took in to his household.
In Sindh province the Pitafi tribe has a strong presence in present day and two elected members to the Sindh Provincial assembly, namely Sardar Ahmed Ali Khan Pitafi and Raise Imdad Ali Pitafi. Initially it is said that the tribe moved from Baluchistan to present day Ghoutki district, however in these modern times the tribe can be found in almost every district of Sindh Province and having significant influential power as well.
In 1867 the art of the tribe still living in the hills was drawn to the plains by land grants. According to the census of 1891 there were 2186 members of the tribe.