EC number 3.11.1.2 ExPASy NiceZyme view | CAS number 153570-68-4 | |
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In enzymology, a phosphonoacetate hydrolase (EC 3.11.1.2) is an enzyme that catalyzes the chemical reaction
phosphonoacetate + H2O
Thus, the two substrates of this enzyme are phosphonoacetate and H2O, whereas its two products are acetate and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on carbon-phosphorus bonds. The systematic name of this enzyme class is phosphonoacetate phosphonohydrolase. This enzyme participates in aminophosphonate metabolism. It employs one cofactor, zinc.
Structural studies
The structure of this enzyme, with the PDB accession code 1EI6, shows it adopts the alkaline phosphatase fold.
References
Phosphonoacetate hydrolase Wikipedia(Text) CC BY-SA