Harman Patil (Editor)

Phenylpyruvate decarboxylase

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EC number
  
4.1.1.43

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
37289-45-5

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a phenylpyruvate decarboxylase (EC 4.1.1.43) is an enzyme that catalyzes the chemical reaction

phenylpyruvate phenylacetaldehyde + CO2

Hence, this enzyme has one substrate, phenylpyruvate, and two products, phenylacetaldehyde and CO2.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is phenylpyruvate carboxy-lyase (phenylacetaldehyde-forming). This enzyme is also called phenylpyruvate carboxy-lyase. This enzyme participates in phenylalanine and tryptophan metabolism.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2NXW.

References

Phenylpyruvate decarboxylase Wikipedia


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