Pregnancycategory AU: C ATC code N05AC01 (WHO) Molar mass 365.49 g/mol | Routes ofadministration Oral Biological half-life 12 h | |
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Legal status AU: S4 (Prescription only)CA: ℞-onlyUK: POM (Prescription only)In general: ℞ (Prescription only) Metabolism | ||
Periciazine (INN), also known as pericyazine (BAN) or propericiazine, is a drug that belongs to the phenothiazine class of typical antipsychotics.
Contents
Pericyazine is not approved for sale in the United States. It is commonly sold in Canada and Russia under the tradename Neuleptil and in United Kingdom and Australia under the tradename Neulactil.
Medical Uses
The primary uses of pericyazine include in the short-term treatment of severe anxiety or tension and in the maintenance treatment of psychotic disorders such as schizophrenia. There is insufficient evidence to determine whether periciazine is more or less effective than other antipsychotics.
Periciazine has also been studied in the treatment of opioid dependence.
Adverse effects
Pericyazine is a rather sedating and anticholinergic antipsychotic, and despite being classed with the typical antipsychotics, its risk of extrapyramidal side effects is comparatively low. It has a relatively high risk of causing hyperprolactinaemia and a moderate risk of causing weight gain and orthostatic hypotension.