Supriya Ghosh (Editor)

Pendetide

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Formula
  
C31H47N7O14

Molar mass
  
741.318 g/mol

Pendetide

Pendetide (GYK-DTPA) is a chelating agent. It consists of pentetic acid (DTPA) linked to the tripeptide glycine (G) – -tyrosine (Y) – -lysine (K).

Use

The following monoclonal antibodies are linked to pendetide to chelate a radionuclide, indium-111. The antibodies selectively bind to certain tumour cells, and the radioactivity is then used for imaging of the tumours.

  • Indium (111In) capromab pendetide (prostate cancer)
  • Indium (111In) satumomab pendetide (other cancer types)

    • References

    Pendetide Wikipedia
    (Text) CC BY-SA