Pearl is a surname. Notable people with the surname include:
Bruce Pearl (born 1960), American college basketball coach
Daniel Pearl (1963–2002), American journalist who was kidnapped and murdered in Pakistan
Judea Pearl (born 1936), computer scientist and philosopher
Minnie Pearl (1912–1996), American country comedian
Raymond Pearl (1879–1940), American biologist
Steven Pearl (born 1955), American comedian
Richard Perle (born 1941), American political advisor
