Entrez 5784 | Ensembl ENSG00000152104 | |
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Aliases PTPN14, PEZ, PTP36, protein tyrosine phosphatase, non-receptor type 14 External IDs MGI: 102467 HomoloGene: 3941 GeneCards: PTPN14 | ||
Tyrosine-protein phosphatase non-receptor type 14 is an enzyme that in humans is encoded by the PTPN14 gene.
Contents
Function
The protein encoded by this gene is a member of the PTP family and PTPN14 subfamily of tyrosine protein phosphatases. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. The specific function of this PTP has not yet been determined.
Interactions
PTPN14 has been shown to interact with Beta-catenin.
References
PTPN14 Wikipedia(Text) CC BY-SA