Species Human Entrez 8000 | Human Mouse Ensembl ENSG00000167653 | |
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Aliases PSCA, PRO232, prostate stem cell antigen External IDs MGI: 1919623 HomoloGene: 4150 GeneCards: PSCA | ||
Prostate stem cell antigen is a protein that in humans is encoded by the PSCA gene.
This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene has a nonsynonymous nucleotide polymorphism at its start codon.
Clinical significance
This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas.
References
PSCA (gene) Wikipedia(Text) CC BY-SA