Species Human Entrez 5558 | Human Mouse Ensembl ENSG00000146143 | |
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Aliases PRIM2, PRIM2A, p58, primase (DNA) subunit 2 External IDs MGI: 97758 HomoloGene: 731 GeneCards: PRIM2 | ||
DNA primase large subunit is an enzyme that in humans is encoded by the PRIM2 gene.
The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the large, 58 kDa primase subunit.
References
PRIM2 Wikipedia(Text) CC BY-SA