Trisha Shetty (Editor)

PPP2R5D

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Species
  
Human

Entrez
  
5528

Human
  
Mouse

Ensembl
  
ENSG00000112640

PPP2R5D

Aliases
  
PPP2R5D, B56D, MRD35, protein phosphatase 2 regulatory subunit B'delta

External IDs
  
MGI: 2388481 HomoloGene: 37661 GeneCards: PPP2R5D

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform is an enzyme that in humans is encoded by the PPP2R5D gene.

Contents

Function

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.

Interactions

PPP2R5D has been shown to interact with:

  • HAND2,
  • PPP2CA,
  • PPP2R1B, and
  • liprin-alpha-1.
  • References

    PPP2R5D Wikipedia