Species Human Entrez 5527 | Human Mouse Ensembl ENSG00000078304 | |
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Aliases PPP2R5C, B56G, PR61G, protein phosphatase 2 regulatory subunit B'gamma External IDs HomoloGene: 135298 GeneCards: PPP2R5C | ||
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform is an enzyme that in humans is encoded by the PPP2R5C gene.
Contents
Function
The product of this gene belongs to the Protein phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.
Interactions
PPP2R5C has been shown to interact with PPP2R1B and PPP2CA.