Kalpana Kalpana (Editor)

POLR2J

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Species
  
Human

Entrez
  
5439

Human
  
Mouse

Ensembl
  
ENSG00000005075

POLR2J

Aliases
  
POLR2J, POLR2J1, RPB11, RPB11A, RPB11m, hRPB14, polymerase (RNA) II subunit J

External IDs
  
MGI: 109582 HomoloGene: 4542 GeneCards: POLR2J

DNA-directed RNA polymerase II subunit RPB11-a is an enzyme that in humans is encoded by the POLR2J gene.

Contents

Function

This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene exists as a heterodimer with another polymerase subunit; together they form a core subassembly unit of the polymerase. Two similar genes are located nearby on chromosome 7q22.1 and a pseudogene is found on chromosome 7p13.

Interactions

POLR2J has been shown to interact with:

  • Apoptosis antagonizing transcription factor,
  • POLR2C, and
  • SATB1.
  • References

    POLR2J Wikipedia