Species Human Entrez 5426 | Human Mouse Ensembl ENSG00000177084 | |
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Aliases POLE, CRCS12, FILS, POLE1, polymerase (DNA) epsilon, catalytic subunit External IDs MGI: 1196391 HomoloGene: 4539 GeneCards: POLE | ||
DNA polymerase epsilon catalytic subunit is an enzyme that in humans is encoded by the POLE gene. It is the central catalytic subunit of DNA polymerase epsilon.
Contents
Clinical significance
POLE, along with POLD1, has recently been associated with multiple adenoma.
Interactions
POLE has been shown to interact with RAD17.
References
POLE (gene) Wikipedia(Text) CC BY-SA