Entrez 5324 | Ensembl ENSG00000181690 | |
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Aliases PLAG1, PSA, SGPA, ZNF912, PLAG1 zinc finger External IDs MGI: 1891916 HomoloGene: 1993 GeneCards: PLAG1 | ||
Function
Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas.
Interactions
PLAG1 has been shown to interact with Karyopherin alpha 2.
References
PLAG1 Wikipedia(Text) CC BY-SA