Species Human Entrez 9033 | Human Mouse Ensembl ENSG00000107593 | |
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Aliases PKD2L1, PCL, PKD2L, PKDL, TRPP3, polycystin 2 like 1, transient receptor potential cation channel External IDs MGI: 1352448 HomoloGene: 22946 GeneCards: PKD2L1 | ||
Polycystic kidney disease 2-like 1 protein also known as transient receptor potential polycystic 3 (TRPP3) is a protein that in humans is encoded by the PKD2L1 gene.
Contents
Function
TRPP3 is a member of the polycystin protein family. TRPP3 contains multiple transmembrane domains, and cytoplasmic N- and C-termini. TRPP3 may be an integral membrane protein involved in cell-cell/matrix interactions. TRPP3 functions as a calcium-regulated nonselective cation channel. Alternative splice variants have been described but their full length sequences have not been determined.
Interactions
PKD2L1 has been shown to interact with TNNI3.
References
PKD2L1 Wikipedia(Text) CC BY-SA