Entrez 116154 | Ensembl ENSG00000087495 | |
Aliases PHACTR3, C20orf101, H17739, PPP1R123, SCAPIN1, SCAPININ, phosphatase and actin regulator 3 External IDs MGI: 1921439 HomoloGene: 14482 GeneCards: PHACTR3 | ||
Phosphatase and actin regulator 3 is an enzyme that in humans is encoded by the PHACTR3 gene.
Contents
Function
The protein encoded by this gene is associated with the nuclear scaffold in proliferating cells. It was found to bind to the catalytic subunit of protein phosphatase-1 (PP1) and inhibit PP1 activity, suggesting that this protein may function as a regulatory subunit of PP1. Alternative splicing at this locus results in several transcript variants encoding different isoforms.
Interactions
PHACTR3 has been shown to interact with PPP1CA.
References
PHACTR3 Wikipedia(Text) CC BY-SA