Entrez 57107 | Ensembl ENSG00000164494 | |
Aliases PDSS2, C6orf210, COQ10D3, DLP1, bA59I9.3, hDLP1, prenyl (decaprenyl) diphosphate synthase, subunit 2 External IDs MGI: 1918615 HomoloGene: 56885 GeneCards: PDSS2 | ||
Decaprenyl-diphosphate synthase subunit 2 (PDSS2) is a protein that in humans is encoded by the PDSS2 gene.
Contents
Function
The protein encoded by this gene is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis.
Clinical significance
It may be associated with Coenzyme Q10 deficiency.
References
PDSS2 Wikipedia(Text) CC BY-SA