Kalpana Kalpana (Editor)

PD 144418

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CAS Number
  
154130-99-1

3D model (Jmol)
  
Interactive image

ChemSpider ID
  
7992981

Formula
  
C18H22N2O

Molar mass
  
282.38 g/mol

PD 144418 or 1,2,3,6-tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine is a potent and selective ligand for the sigma-1 receptor, with a reported binding affinity of Ki = 0.08 ± 0.01 nM, and 17 212 times selectivity over the sigma-2 receptor.

References

PD 144418 Wikipedia