Harman Patil (Editor)

PARD6B

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Species
  
Human

Entrez
  
84612

Human
  
Mouse

Ensembl
  
ENSG00000124171

PARD6B

Aliases
  
PARD6B, PAR6B, par-6 family cell polarity regulator beta

External IDs
  
MGI: 2135605 HomoloGene: 23302 GeneCards: PARD6B

Partitioning defective 6 homolog beta is a protein that in humans is encoded by the PARD6B gene.

Contents

Function

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex.

Interactions

PARD6B has been shown to interact with:

  • CDC42,
  • Protein kinase Mζ,
  • RAC1, and
  • RHOQ.

    • References

    PARD6B Wikipedia
    (Text) CC BY-SA


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