Entrez 53354 | Ensembl ENSG00000152782 | |
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External IDs MGI: 1922985 HomoloGene: 56979 GeneCards: PANK1 |
Pantothenate kinase 1 is an enzyme that in humans is encoded by the PANK1 gene.
This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, have been identified.
References
PANK1 Wikipedia(Text) CC BY-SA