Oxley is a Yorkshire surname. Notable people with the surname include:
Adam Oxley, Australian rules footballer
Alan Oxley, Australian diplomat.
Alan Rice-Oxley, British flying ace during World War I
Bernard Oxley, English footballer
Bill Oxley, English professional rugby league footballer
Cyril Oxley, English footballer
David Oxley, English actor
George Oxley, political figure in colonial Nova Scotia
Harrison Oxley, English organist
Henry Oxley, Canadian-born Major League baseball player
James Oxley, Australian–American mathematician
James Macdonald Oxley (1855–1907), Canadian lawyer and an author of books for boys
Jeremy Oxley, Australian musician, guitarist for 1980s band the Sunnyboys
John Oxley (1783–1828), Australian explorer
John Oxley (disambiguation), several more people
Joseph Oxley, political figure in colonial Nova Scotia
Joseph W. Oxley, American Republican Party politician
Lawrence A. Oxley, American community leader appointed to Roosevelt's "Black Cabinet"
Melanie Oxley, Australian musician and songwriter
Mark Oxley. English professional footballer
Mark Rice-Oxley, English journalist
Mike Oxley, United States congressman and co-sponsor to the Sarbanes–Oxley Act
Paul Oxley, English songwriter/lyricist/producer living in Finland
Philip Oxley, English cricketer
Peter Oxley, Australian musician, bass player for The Sunnyboys
Roy Oxley, British television set designer
Scott Oxley (born 1976), English professional footballer
Tanya Oxley, Barbadian track and field sprinter
Tim Rice-Oxley, British musician
Tony Oxley, British jazz drummer
W. Oxley, eighteenth century English professional cricketer