Trade names Xynor CAS ID 16773-42-5 | Routes ofadministration Oral Molar mass 219.625 g/mol | |
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AHFS/Drugs.com International Drug Names ATC code G01AF06 (WHO) J01XD03 (WHO) P01AB03 (WHO) QP51AA03 (WHO) Metabolism Excretion 85% of single oral dose is eliminated with 5 days - Urine (63%) and Feces (22%) | ||
Medical vocabulary what does ornidazole mean
Ornidazole is a drug that cures some protozoan infections. It has been investigated for use in Crohn's disease after bowel resection.
Contents
Synthesis is a straightforward reaction between 2-methyl-nitroimidazole and epichlorohydrin under acid catalyst conditions.
Mechanism Of Action & Susceptible Organisms
After passive absorption into bacterium cell, the nitro group of ornidazole is reduced to amine group by ferrodoxin type redox system. The formation of redox intermediate intracellular metabolites is believed to be the key component of microorganism killing for Ornidazole. The drug is active against anaerobic bacteria viz. Peptostreptococcus, Clostridium, B. fragilis, Prevotella, Porphyronomas, Fusobacterium and protozoa viz. E. histolytica, T. vaginalis, G. intestinalis etc.
References
Ornidazole Wikipedia(Text) CC BY-SA