Opus 100 is Isaac Asimov's one hundredth book. It was published by Houghton Mifflin on 16 October 1969. Asimov chose to celebrate the publication of his hundredth book by writing about his previous 99 books, including excerpts from short stories and novels, as well as nonfiction articles and books. Opus 100 also includes five complete science fiction stories and one complete science essay.
Introduction
Part 1. Astronomy
Excerpt from "The Callistan Menace"Excerpt from Lucky Starr and the Moons of JupiterExcerpt from "View from Amalthea" from The Solar System and BackExcerpt from Lucky Starr and the Oceans of VenusExcerpt from "The Martian Way"Excerpt from The UniverseExcerpt from GalaxiesPart 2. Robots
Excerpt from "The Perfect Machine" from Today and Tomorrow and ...Excerpt from "Strange Playfellow" (usually titled "Robbie")Excerpt from "Liar!"Excerpt from "Runaround"Excerpt from "I, Robot"Excerpt from The Intelligent Man's Guide to Science"The Last Question"Part 3. Mathematics
Excerpt from Realm of NumbersExcerpt from Quick and Easy Math"The Feeling of Power"Part 4. Physics
Excerpt from Asimov's Biographical Encyclopedia of Science and TechnologyExcerpt from the introduction to Only a TrillionExcerpt from The NeutrinoExcerpt from "Superneutron"Part 5. Chemistry
Excerpt from "The Sound of Panting" from Only a TrillionExcerpt from Biochemistry and Human MetabolismExcerpt from The Chemicals of LifeExcerpt from The Noble Gases"Thiotimoline and the Space Age"Excerpt from The Kinetics of the Reaction Inactivation of Tyrosinase during its Catalysis of the Aerobic Oxidation of CatecholPart 6. Biology
Excerpt from The Wellsprings of LifeExcerpt from PhotosynthesisPart 7. Words
Excerpts from Words of Science"Helium""Idiot""RH Negative"Excerpts from Words on the Map"New Jersey""Philadelphia""Virgin Islands"Excerpts from Words from History"Bloody Shirt""Mob""Potemkin Village"Part 8. History
Excerpt from The Greeks"The Spartan Way of Life"Excerpt from The Roman RepublicExcerpt from The EgyptiansExcerpt from The Near EastExcerpt from "There's Nothing Like a Good Foundation" from Asimov on Science FictionExcerpt from "The Dead Hand"Part 9. The Bible
Excerpt from Asimov's Guide to the Bible"Twelve Point Three Six Nine" from Science, Numbers, and IPart 10. Short Shorts
Excerpt from Please Explain"On Prediction", an introduction to Future Tense edited by Richard Curtis"An Uncompromising View", a review of Mechanical Men by Dean E. Wooldridge"Dreamworld"Part 11. Humor
"The Holmes-Ginsbook Device"Appendix: My Hundred Books
Algis Budrys gave Opus 100 a mixed review, saying "the book as a whole demands so many shifts of personality and attitude in the reader that no one, not even Asimov, could keep up with them comfortably."