Omega amidase

In enzymology, an omega-amidase (EC 3.5.1.3) is an enzyme that catalyzes the chemical reaction

a monoamide of a dicarboxylic acid + H₂O ⇌ a dicarboxylate + NH₃

Thus, the two substrates of this enzyme are monoamide of a dicarboxylic acid and H₂O, whereas its two products are dicarboxylate and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is omega-amidodicarboxylate amidohydrolase. This enzyme is also called alpha-keto acid-omega-amidase. This enzyme participates in glutamate metabolism and alanine and aspartate metabolism.